Description

PE-22-28 10mg Research Peptide Vial

PE-22-28 Sold as 10 MG Lyophilized Powder. Bacteriostatic water is not included.

This product is strictly intended for research and medical purposes by qualified professionals.

PE-22-28 is a highly researched synthetic mini-spadin heptapeptide renowned as a potent and selective TREK-1 potassium channel inhibitor (IC50 0.12 nM). Studies suggest the PE-22-28 peptide may deliver rapid-acting antidepressant effects, accelerate hippocampal neurogenesis in as little as 4 days, enhance synaptogenesis, boost neuroplasticity, support cognitive function, and provide neuroprotection in stroke and post-stroke depression models. This optimized 7-amino-acid peptide is widely studied for its fast-onset mood benefits, brain repair, and superior stability compared to original spadin.

The PE-22-28 peptide works by selectively blocking TREK-1 channels, increasing neuronal excitability in serotonin pathways, upregulating BDNF expression, activating CREB signaling, and elevating synaptic markers such as PSD-95 and synapsin. Its enhanced stability offers prolonged action duration (up to 23 hours), making the PE-22-28 10mg vial an essential research tool for laboratories exploring next-generation antidepressants, cognitive enhancement, neuroprotection, and rapid neuroregenerative mechanisms.

Note: Products are for laboratory research use only. Not for human consumption.

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